Combination Chemotherapy With or Without Bortezomib in Treating Younger Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or Stage II-IV T-Cell Lymphoblastic Lymphoma

NCT02112916 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

847

Enrollment

NIH

Sponsor class

Conditions

Adult T Acute Lymphoblastic Leukemia
Ann Arbor Stage II Adult Lymphoblastic Lymphoma
Ann Arbor Stage II Childhood Lymphoblastic Lymphoma
Ann Arbor Stage III Adult Lymphoblastic Lymphoma
Ann Arbor Stage III Childhood Lymphoblastic Lymphoma
Ann Arbor Stage IV Adult Lymphoblastic Lymphoma
Ann Arbor Stage IV Childhood Lymphoblastic Lymphoma
Childhood T Acute Lymphoblastic Leukemia

Interventions

DRUG: Bortezomib
DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Daunorubicin
DRUG: Daunorubicin Hydrochloride
DRUG: Dexamethasone
DRUG: Doxorubicin
DRUG: Doxorubicin Hydrochloride
DRUG: Etoposide
DRUG: Hydrocortisone Sodium Succinate
DRUG: Ifosfamide
DRUG: Leucovorin Calcium
DRUG: Mercaptopurine
DRUG: Methotrexate
DRUG: Pegaspargase
RADIATION: Radiation Therapy
DRUG: Thioguanine
DRUG: Vincristine
DRUG: Vincristine Sulfate

Sponsor

National Cancer Institute (NCI)