# Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy

> **NCT02149459** · PHASE1 · UNKNOWN · sponsor: **Sheba Medical Center** · enrollment: 18 (estimated)

## Conditions studied

- Brain Neoplasms

## Interventions

- **RADIATION:** Partial brain re-irradiation.
- **DRUG:** Metformin
- **BEHAVIORAL:** low carbohydrate diet

## Key facts

- **NCT ID:** NCT02149459
- **Lead sponsor:** Sheba Medical Center
- **Sponsor class:** OTHER_GOV
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2014-06
- **Primary completion:** 2018-07
- **Final completion:** 2018-07
- **Target enrollment:** 18 (ESTIMATED)
- **Last updated:** 2017-10-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02149459

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02149459, "Treatment of Recurrent Brain Tumors: Metabolic Manipulation Combined With Radiotherapy". Retrieved via AI Analytics 2026-05-24 from https://api.ai-analytics.org/clinical/NCT02149459. Licensed CC0.

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