# A Study of Adult Outpatients With Opioid Dependence Transitioned From a Daily SL Buprenorphine to Probuphine® Subdermal Implants

> **NCT02180659** · PHASE3 · COMPLETED · sponsor: **Titan Pharmaceuticals** · enrollment: 177 (actual)

## Conditions studied

- Opioid Dependence

## Interventions

- **DRUG:** sublingual buprenorphine tablets
- **DRUG:** Buprenorphine implant
- **DRUG:** placebo implants
- **DRUG:** sublingual placebo tablets

## Key facts

- **NCT ID:** NCT02180659
- **Lead sponsor:** Titan Pharmaceuticals
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-07
- **Primary completion:** 2015-05
- **Final completion:** 2015-05
- **Target enrollment:** 177 (ACTUAL)
- **Last updated:** 2019-01-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02180659

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02180659, "A Study of Adult Outpatients With Opioid Dependence Transitioned From a Daily SL Buprenorphine to Probuphine® Subdermal Implants". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT02180659. Licensed CC0.

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