# Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

> **NCT02186847** · PHASE2 · COMPLETED · sponsor: **NRG Oncology** · enrollment: 170 (actual)

## Conditions studied

- Adenosquamous Lung Carcinoma
- Bronchioloalveolar Carcinoma
- Large Cell Lung Carcinoma
- Lung Adenocarcinoma
- Non-Small Cell Lung Carcinoma
- Recurrent Non-Small Cell Lung Carcinoma
- Squamous Cell Lung Carcinoma
- Stage IIIA Non-Small Cell Lung Cancer
- Stage IIIB Non-Small Cell Lung Cancer

## Interventions

- **RADIATION:** Radiation Therapy
- **DRUG:** Carboplatin
- **DRUG:** Metformin
- **DRUG:** Paclitaxel

## Key facts

- **NCT ID:** NCT02186847
- **Lead sponsor:** NRG Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-08
- **Primary completion:** 2019-04-16
- **Final completion:** 2025-09-04
- **Target enrollment:** 170 (ACTUAL)
- **Last updated:** 2025-10-09

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02186847

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02186847, "Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02186847. Licensed CC0.

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