# Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients

> **NCT02188121** · PHASE4 · COMPLETED · sponsor: **Mclean Hospital** · enrollment: 227 (actual)

## Conditions studied

- Serious Mental Illness
- Schizophrenia
- Schizoaffective Disorder
- Bipolar Disorder
- Cardiovascular Disease
- Major Depressive Disorder
- Psychosis NOS

## Interventions

- **DRUG:** Simvastatin
- **DRUG:** Losartan

## Key facts

- **NCT ID:** NCT02188121
- **Lead sponsor:** Mclean Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-02
- **Primary completion:** 2020-10
- **Final completion:** 2021-10
- **Target enrollment:** 227 (ACTUAL)
- **Last updated:** 2023-01-30

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02188121

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02188121, "Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT02188121. Licensed CC0.

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