# Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma

> **NCT02190838** · PHASE2 · TERMINATED · sponsor: **N.N. Petrov National Medical Research Center of Oncology** · enrollment: 57 (actual)

## Conditions studied

- Melanoma

## Interventions

- **DRUG:** Metformin
- **DRUG:** Melatonin
- **DRUG:** Dacarbazine

## Key facts

- **NCT ID:** NCT02190838
- **Lead sponsor:** N.N. Petrov National Medical Research Center of Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2014-04
- **Primary completion:** 2015-12-12
- **Final completion:** 2018-12-31
- **Target enrollment:** 57 (ACTUAL)
- **Why stopped:** Preliminary terminated due to inefficacy
- **Last updated:** 2019-11-25


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02190838

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02190838, "Comparison of Melatonin or Metformin and Dacarbazine Combination Versus Dacarbazine Alone in Disseminated Melanoma". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02190838. Licensed CC0.

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