# Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults

> **NCT02191579** · PHASE4 · COMPLETED · sponsor: **Allergan** · enrollment: 282 (actual)

## Conditions studied

- Migraine Disorders

## Interventions

- **BIOLOGICAL:** onabotulinumtoxinA
- **DRUG:** Topiramate

## Key facts

- **NCT ID:** NCT02191579
- **Lead sponsor:** Allergan
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-08-05
- **Primary completion:** 2017-05-09
- **Final completion:** 2017-09-01
- **Target enrollment:** 282 (ACTUAL)
- **Last updated:** 2018-06-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02191579

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02191579, "Efficacy and Safety Study of BOTOX® Compared to Topiramate for the Prevention of Chronic Migraine in Adults". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02191579. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*