# A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males

> **NCT02220777** · PHASE1 · COMPLETED · sponsor: **Astellas Pharma Europe B.V.** · enrollment: 72 (actual)

## Conditions studied

- Pharmacokinetics of ASP8477
- Pharmacodynamics of ASP8477

## Interventions

- **DRUG:** ASP8477
- **DRUG:** omeprazole
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02220777
- **Lead sponsor:** Astellas Pharma Europe B.V.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2010-11
- **Primary completion:** 2011-05
- **Final completion:** 2011-05
- **Target enrollment:** 72 (ACTUAL)
- **Last updated:** 2014-08-20


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02220777

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02220777, "A Study to Assess the Effects of Single Ascending Doses (SAD) of ASP8477, the Effect That Food Has on the Drug, and the Interaction Between ASP8477 and Omeprazole in Healthy Postmenopausal Females and Healthy Young Vasectomized Males". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT02220777. Licensed CC0.

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