# Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO)

> **NCT02227446** · PHASE3 · COMPLETED · sponsor: **Major Extremity Trauma Research Consortium** · enrollment: 1036 (actual)

## Conditions studied

- Post Operative Surgical Site Infection

## Interventions

- **DRUG:** Vancomycin antibiotic powder

## Key facts

- **NCT ID:** NCT02227446
- **Lead sponsor:** Major Extremity Trauma Research Consortium
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-10
- **Primary completion:** 2018-06
- **Final completion:** 2019-11
- **Target enrollment:** 1036 (ACTUAL)
- **Last updated:** 2021-06-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02227446

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02227446, "Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO)". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02227446. Licensed CC0.

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