# Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure

> **NCT02235077** · PHASE2 · COMPLETED · sponsor: **Duke University** · enrollment: 360 (actual)

## Conditions studied

- Heart Failure

## Interventions

- **DRUG:** Spironolactone
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02235077
- **Lead sponsor:** Duke University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-12-30
- **Primary completion:** 2016-04-12
- **Final completion:** 2016-06-06
- **Target enrollment:** 360 (ACTUAL)
- **Last updated:** 2017-06-14

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02235077

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02235077, "Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02235077. Licensed CC0.

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