A Phase 1 Study of Oprozomib to Assess Food Effect, Drug-Drug Interaction With Midazolam, and Safety and Tolerability in Patients With Advanced Malignancies
Stopped Why study stopped revised to "A program evaluation identified that the safety profile and pharmacokinetic (PK) characteristics of the formulation used in all oprozomib studies required further optimization and thus enrollment in OPZ009 was halted
Conditions
- Advanced Non-Central Nervous System (CNS) Malignancies
Interventions
- DRUG: Oprozomib
- DRUG: Midazolam
Sponsor
Amgen