Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

NCT02250937 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

116

Enrollment

OTHER

Sponsor class

Conditions

Acute Myeloid Leukemia
Myelodysplastic Syndrome

Interventions

PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Busulfan
DRUG: Cladribine
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
PROCEDURE: Peripheral Blood Stem Cell Transplantation
OTHER: Pharmacological Study
DRUG: Venetoclax

Sponsor

M.D. Anderson Cancer Center

Collaborators

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