JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary Myelofibrosis

NCT02251821 · clinicaltrials.gov ↗

PHASE2

Phase

COMPLETED

Status

61

Enrollment

OTHER

Sponsor class

Conditions

Primary Myelofibrosis
Secondary Myelofibrosis

Interventions

PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Busulfan
DRUG: Cyclophosphamide
DRUG: Fludarabine Phosphate
OTHER: Laboratory Biomarker Analysis
DRUG: Melphalan
DRUG: Methotrexate
DRUG: Mycophenolate Mofetil
DRUG: Ruxolitinib
DRUG: Tacrolimus
RADIATION: Total-Body Irradiation
PROCEDURE: Umbilical Cord Blood Transplantation

Sponsor

Fred Hutchinson Cancer Center

Collaborators

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