# Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin

> **NCT02266329** · PHASE1,PHASE2 · COMPLETED · sponsor: **VA Office of Research and Development** · enrollment: 89 (actual)

## Conditions studied

- Posttraumatic Headache
- Combat Disorders
- Post Concussion Syndrome
- Headache
- Mild Traumatic Brain Injury
- Posttraumatic Migraine

## Interventions

- **DRUG:** prazosin hydrochloride
- **DRUG:** placebo

## Key facts

- **NCT ID:** NCT02266329
- **Lead sponsor:** VA Office of Research and Development
- **Sponsor class:** FED
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2016-01-04
- **Primary completion:** 2023-05-31
- **Final completion:** 2023-09-30
- **Target enrollment:** 89 (ACTUAL)
- **Last updated:** 2026-03-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02266329

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02266329, "Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT02266329. Licensed CC0.

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