# Investigating the Role of the Polyol Pathway in the Central Nervous System

> **NCT02272556** · NA · COMPLETED · sponsor: **Yale University** · enrollment: 138 (actual)

## Conditions studied

- Hyperglycemia

## Interventions

- **OTHER:** Brain MRS during hyperglycemic clamp
- **OTHER:** Analysis of Metabolites in cerebrospinal fluid

## Key facts

- **NCT ID:** NCT02272556
- **Lead sponsor:** Yale University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-02
- **Primary completion:** 2022-05-18
- **Final completion:** 2022-05-18
- **Target enrollment:** 138 (ACTUAL)
- **Last updated:** 2022-08-18

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02272556

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02272556, "Investigating the Role of the Polyol Pathway in the Central Nervous System". Retrieved via AI Analytics 2026-07-12 from https://api.ai-analytics.org/clinical/NCT02272556. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
