# Progesterone Amplifies Estrogen-stimulated Growth Hormone Secretion in Older Women

> **NCT02272647** · PHASE1 · COMPLETED · sponsor: **Mayo Clinic** · enrollment: 47 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** IM Saline Placebo (0.25 ml)
- **DRUG:** IM Estradiol valerate (2.5 mg)
- **DRUG:** IM Saline Placebo (0.5 ml)
- **DRUG:** IM Estradiol valerate (5.0 mg)
- **DRUG:** Oral Micronized Progesterone
- **DRUG:** Oral Placebo
- **DRUG:** Ghrelin (0.3 ug/kg)
- **DRUG:** Medroxyprogesterone - Acetate
- **DRUG:** Oral Placebo

## Key facts

- **NCT ID:** NCT02272647
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-12
- **Primary completion:** 2016-12
- **Final completion:** 2018-02
- **Target enrollment:** 47 (ACTUAL)
- **Last updated:** 2018-03-22


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02272647

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02272647, "Progesterone Amplifies Estrogen-stimulated Growth Hormone Secretion in Older Women". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02272647. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*