# De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

> **NCT02281955** · PHASE2 · COMPLETED · sponsor: **UNC Lineberger Comprehensive Cancer Center** · enrollment: 115 (actual)

## Conditions studied

- Carcinoma, Squamous Cell
- Head and Neck Neoplasms
- Oropharyngeal Neoplasms

## Interventions

- **RADIATION:** Intensity Modulated Radiotherapy (IMRT)
- **DRUG:** Cisplatin (or alternative)
- **PROCEDURE:** Assessment for surgical evaluation

## Key facts

- **NCT ID:** NCT02281955
- **Lead sponsor:** UNC Lineberger Comprehensive Cancer Center
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-08
- **Primary completion:** 2019-11
- **Final completion:** 2024-11-24
- **Target enrollment:** 115 (ACTUAL)
- **Last updated:** 2025-01-07


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02281955

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02281955, "De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02281955. Licensed CC0.

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