# Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty

> **NCT02284386** · PHASE4 · COMPLETED · sponsor: **Pacira Pharmaceuticals, Inc** · enrollment: 15 (actual)

## Conditions studied

- Pain

## Interventions

- **DRUG:** Bupivacaine SNB
- **DRUG:** EXPAREL Infiltration

## Key facts

- **NCT ID:** NCT02284386
- **Lead sponsor:** Pacira Pharmaceuticals, Inc
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-12
- **Primary completion:** 2015-03
- **Final completion:** 2015-03
- **Target enrollment:** 15 (ACTUAL)
- **Last updated:** 2021-03-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02284386

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02284386, "Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02284386. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*