# Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402)

> **NCT02288078** · PHASE2 · UNKNOWN · sponsor: **Clinical Research Support Center Kyush** · enrollment: 74 (estimated)

## Conditions studied

- Rectal Cancer

## Interventions

- **OTHER:** General condition
- **OTHER:** Blood pressure
- **OTHER:** Patient Reported Outcome
- **OTHER:** Clinical findings
- **OTHER:** Hematology/blood chemistry
- **OTHER:** Coagulation and fibrinolysis system
- **OTHER:** Urinalysis
- **OTHER:** Medication check
- **OTHER:** Adverse event
- **OTHER:** Thyroid function test
- **OTHER:** Contrast-enhanced torso CT
- **OTHER:** Brain MRI
- **DRUG:** Dexamethasone
- **DRUG:** Regorafenib
- **DRUG:** Placebo
- **DRUG:** Proton pump inhibitor

## Key facts

- **NCT ID:** NCT02288078
- **Lead sponsor:** Clinical Research Support Center Kyush
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2014-10
- **Primary completion:** 2015-09
- **Final completion:** 2016-09
- **Target enrollment:** 74 (ESTIMATED)
- **Last updated:** 2014-11-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02288078

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02288078, "Oral Steroids for Regorafenib-induced Fatigue/Malaise in Unresectable mCRC (KSCC1402/HGCSG1402)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02288078. Licensed CC0.

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