Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Conditions

• Acute Lymphoblastic Leukemia (ALL)

Interventions

• DRUG: Carfilzomib
• DRUG: Dexamethasone
• DRUG: Mitoxantrone
• DRUG: PEG-asparaginase
• DRUG: Vincristine
• DRUG: Intrathecal (IT) Methotrexate
• DRUG: Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate)
• DRUG: 6-Mercaptopurine
• DRUG: Cyclophosphamide
• DRUG: Cytarabine
• DRUG: Daunorubicin

Sponsor

Amgen

Collaborators

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