Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

NCT02311933 · clinicaltrials.gov ↗

PHASE2

Phase

ACTIVE_NOT_RECRUITING

Status

81

Enrollment

NIH

Sponsor class

Conditions

Recurrent Breast Carcinoma
Stage III Breast Cancer AJCC v7
Stage IIIA Breast Cancer AJCC v7
Stage IIIB Breast Cancer AJCC v7
Stage IIIC Breast Cancer AJCC v7
Stage IV Breast Cancer AJCC v6 and v7

Interventions

DRUG: Endoxifen Hydrochloride
OTHER: Laboratory Biomarker Analysis
OTHER: Pharmacological Study
DRUG: Tamoxifen Citrate

Sponsor

National Cancer Institute (NCI)