Intensity Modulated Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients With Relapsed Hematologic Cancers Undergoing a Second Donor Stem Cell Transplant
Stopped Enrollment on hold pending amendment
Conditions
- Previously Treated Myelodysplastic Syndrome
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Recurrent Hematologic Malignancy
Interventions
- DRUG: Fludarabine Phosphate
- DRUG: Melphalan
- RADIATION: Intensity-Modulated Radiation Therapy
- RADIATION: Total Marrow Irradiation
- PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
- PROCEDURE: Peripheral Blood Stem Cell Transplantation
- PROCEDURE: Allogeneic Bone Marrow Transplantation
- DRUG: Tacrolimus
- DRUG: Mycophenolate Mofetil
- OTHER: Laboratory Biomarker Analysis
Sponsor
University of Chicago
Collaborators