# Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)

> **NCT02339584** · PHASE3 · COMPLETED · sponsor: **Alcon Research** · enrollment: 493 (actual)

## Conditions studied

- Open-Angle Glaucoma
- Ocular Hypertension

## Interventions

- **DRUG:** Brinzolamide 10 mg/mL / Brimonidine 2 mg/mL fixed combination eye drops, suspension
- **DRUG:** Brinzolamide 10 mg/mL eye drops, suspension
- **DRUG:** Brimonidine 2 mg/mL eye drops, solution
- **DRUG:** Vehicle

## Key facts

- **NCT ID:** NCT02339584
- **Lead sponsor:** Alcon Research
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-04-14
- **Primary completion:** 2016-11-01
- **Final completion:** 2016-11-01
- **Target enrollment:** 493 (ACTUAL)
- **Last updated:** 2018-07-02


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02339584

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02339584, "Efficacy and Safety of Brinzolamide/Brimonidine Fixed Combination BID Compared to Brinzolamide BID Plus Brimonidine BID in Subjects With Open-Angle Glaucoma (OAG) or Ocular Hypertension (OHT)". Retrieved via AI Analytics 2026-06-05 from https://api.ai-analytics.org/clinical/NCT02339584. Licensed CC0.

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