# C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer

> **NCT02344810** · PHASE1,PHASE2 · WITHDRAWN · sponsor: **Eastern Cooperative Oncology Group**

## Conditions studied

- Adenocarcinoma of the Esophagus
- Adenocarcinoma of the Gastroesophageal Junction
- Diffuse Adenocarcinoma of the Stomach
- Gastrointestinal Cancer
- Intestinal Adenocarcinoma of the Stomach
- Mixed Adenocarcinoma of the Stomach
- Stage IIIA Esophageal Cancer
- Stage IIIA Gastric Cancer
- Stage IIIB Esophageal Cancer
- Stage IIIB Gastric Cancer
- Stage IIIC Esophageal Cancer
- Stage IIIC Gastric Cancer
- Stage IV Esophageal Cancer
- Stage IV Gastric Cancer

## Interventions

- **DRUG:** c-Met inhibitor AMG 337
- **OTHER:** placebo
- **DRUG:** oxaliplatin
- **DRUG:** leucovorin calcium
- **DRUG:** fluorouracil
- **OTHER:** pharmacological study
- **OTHER:** laboratory biomarker analysis

## Key facts

- **NCT ID:** NCT02344810
- **Lead sponsor:** Eastern Cooperative Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** WITHDRAWN
- **Start date:** 2015-03-06
- **Primary completion:** 2015-03-06
- **Final completion:** —
- **Target enrollment:** 0 (ACTUAL)
- **Why stopped:** The study did not open to accrual. No start date and no completion dates.
- **Last updated:** 2023-05-25

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02344810

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02344810, "C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT02344810. Licensed CC0.

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