Preventing Sickle Cell Kidney Disease

Stopped Estimated GFR was determined not to be a reliable endpoint for this study. We identified significant variabilty in annual eGFR that it became inappropriate to randomize to a medication but use EGFR as the primary endpoint.

Conditions

• Anemia, Sickle Cell
• Sickle Cell Disease
• Kidney Disease
• Hypertension
• Proteinuria

Interventions

• DRUG: Losartan
• DRUG: Losartan

Sponsor

University of Alabama at Birmingham

Collaborators

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