# A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]

> **NCT02377947** · — · COMPLETED · sponsor: **Abbott** · enrollment: 50 (actual)

## Conditions studied

- Hepatic Encephalopathy

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT02377947
- **Lead sponsor:** Abbott
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2015-12
- **Primary completion:** 2016-03
- **Final completion:** 2016-03
- **Target enrollment:** 50 (ACTUAL)
- **Last updated:** 2020-02-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02377947

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02377947, "A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02377947. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*