# Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

> **NCT02381561** · PHASE1 · ACTIVE_NOT_RECRUITING · sponsor: **National Cancer Institute (NCI)** · enrollment: 19 (actual)

## Conditions studied

- Advanced Bile Duct Carcinoma
- Stage II Esophageal Cancer AJCC v7
- Stage II Pancreatic Cancer AJCC v6 and v7
- Stage IIA Esophageal Cancer AJCC v7
- Stage IIA Pancreatic Cancer AJCC v6 and v7
- Stage IIB Esophageal Cancer AJCC v7
- Stage IIB Pancreatic Cancer AJCC v6 and v7
- Stage III Colon Cancer AJCC v7
- Stage III Esophageal Cancer AJCC v7
- Stage III Gastric Cancer AJCC v7
- Stage III Liver Cancer
- Stage III Pancreatic Cancer AJCC v6 and v7
- Stage III Rectal Cancer AJCC v7
- Stage III Small Intestinal Cancer AJCC v7
- Stage IIIA Colon Cancer AJCC v7
- Stage IIIA Esophageal Cancer AJCC v7
- Stage IIIA Gastric Cancer AJCC v7
- Stage IIIA Rectal Cancer AJCC v7
- Stage IIIA Small Intestinal Cancer AJCC v7
- Stage IIIB Colon Cancer AJCC v7
- Stage IIIB Esophageal Cancer AJCC v7
- Stage IIIB Gastric Cancer AJCC v7
- Stage IIIB Rectal Cancer AJCC v7
- Stage IIIB Small Intestinal Cancer AJCC v7
- Stage IIIC Colon Cancer AJCC v7
- Stage IIIC Esophageal Cancer AJCC v7
- Stage IIIC Gastric Cancer AJCC v7
- Stage IIIC Rectal Cancer AJCC v7
- Stage IV Colon Cancer AJCC v7
- Stage IV Esophageal Cancer AJCC v7
- Stage IV Gastric Cancer AJCC v7
- Stage IV Liver Cancer
- Stage IV Pancreatic Cancer AJCC v6 and v7
- Stage IV Rectal Cancer AJCC v7
- Stage IV Small Intestinal Cancer AJCC v7
- Stage IVA Colon Cancer AJCC v7
- Stage IVA Liver Cancer
- Stage IVA Rectal Cancer AJCC v7
- Stage IVB Colon Cancer AJCC v7
- Stage IVB Liver Cancer
- Stage IVB Rectal Cancer AJCC v7

## Interventions

- **RADIATION:** Intensity-Modulated Radiation Therapy
- **OTHER:** Laboratory Biomarker Analysis
- **OTHER:** Pharmacological Study
- **DRUG:** Ropidoxuridine

## Key facts

- **NCT ID:** NCT02381561
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2016-02-01
- **Primary completion:** 2018-11-08
- **Final completion:** 2027-03-14
- **Target enrollment:** 19 (ACTUAL)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02381561

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02381561, "Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT02381561. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*