A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

NCT02418585 · clinicaltrials.gov ↗

PHASE3

Phase

COMPLETED

Status

236

Enrollment

INDUSTRY

Sponsor class

Conditions

Treatment-resistant Depression

Interventions

DRUG: Esketamine
DRUG: Placebo
DRUG: Duloxetine (Oral Antidepressant)
DRUG: Escitalopram (Oral antidepressant)
DRUG: Sertraline (Oral Antidepressant)
DRUG: Venlafaxine Extended Release (XR) (Oral Antidepressant)

Sponsor

Janssen Research & Development, LLC