Ruxolitinib Phosphate or Dasatinib With Chemotherapy in Treating Patients With Relapsed or Refractory Philadelphia Chromosome-Like Acute Lymphoblastic Leukemia

NCT02420717 · clinicaltrials.gov ↗

PHASE2

Phase

TERMINATED

Status

11

Enrollment

OTHER

Sponsor class

Stopped Study was closed early due to low accrual and lack of response.

Conditions

Recurrent B Acute Lymphoblastic Leukemia
Recurrent Ph-Like Acute Lymphoblastic Leukemia
Refractory B Acute Lymphoblastic Leukemia
Refractory Ph-Like Acute Lymphoblastic Leukemia

Interventions

DRUG: Cyclophosphamide
DRUG: Cytarabine
DRUG: Dasatinib
DRUG: Dexamethasone
DRUG: Doxorubicin
OTHER: Laboratory Biomarker Analysis
DRUG: Leucovorin
DRUG: Mercaptopurine
DRUG: Methotrexate
DRUG: Prednisone
BIOLOGICAL: Rituximab
DRUG: Ruxolitinib Phosphate
DRUG: Vincristine

Sponsor

M.D. Anderson Cancer Center

Collaborators

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