A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression

NCT02422186 · clinicaltrials.gov ↗

PHASE3

Phase

COMPLETED

Status

139

Enrollment

INDUSTRY

Sponsor class

Conditions

Depressive Disorder, Treatment-Resistant

Interventions

DRUG: Esketamine
DRUG: Placebo
DRUG: Duloxetine (Oral Antidepressant)
DRUG: Escitalopram (Oral Antidepressant)
DRUG: Sertraline (Oral Antidepressant)
DRUG: Venlafaxine Extended Release (XR) (New Antidepressant)

Sponsor

Janssen Research & Development, LLC