# Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers

> **NCT02431442** · PHASE1 · COMPLETED · sponsor: **Rhythm Pharmaceuticals, Inc.** · enrollment: 57 (actual)

## Conditions studied

- Overweight
- Obese

## Interventions

- **DRUG:** RM-493
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02431442
- **Lead sponsor:** Rhythm Pharmaceuticals, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2012-01
- **Primary completion:** 2014-01
- **Final completion:** 2014-01
- **Target enrollment:** 57 (ACTUAL)
- **Last updated:** 2015-05-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02431442

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02431442, "Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT02431442. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*