Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia
Conditions
- Adult Acute Lymphoblastic Leukemia in Complete Remission
- Acute Myeloid Leukemia in Remission
- Previously Treated Myelodysplastic Syndrome
- Recurrent Adult Acute Lymphoblastic Leukemia
- Recurrent Adult Acute Myeloid Leukemia
- Recurrent Childhood Acute Lymphoblastic Leukemia
- Recurrent Childhood Acute Myeloid Leukemia
- Childhood Acute Lymphoblastic Leukemia in Complete Remission
Interventions
- PROCEDURE: Bone Marrow Transplantation
- DRUG: Cyclophosphamide
- DRUG: Fludarabine Phosphate
- OTHER: Laboratory Biomarker Analysis
- DRUG: Mycophenolate Mofetil
- PROCEDURE: Peripheral Blood Stem Cell Transplantation
- DRUG: Tacrolimus
- RADIATION: Total Marrow Irradiation
Sponsor
City of Hope Medical Center
Collaborators