# Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial

> **NCT02450253** · PHASE2 · COMPLETED · sponsor: **St George's, University of London** · enrollment: 55 (actual)

## Conditions studied

- Dementia, Vascular

## Interventions

- **DRUG:** Tadalafil
- **DRUG:** Placebo
- **BEHAVIORAL:** Cognitive functioning tests
- **BEHAVIORAL:** Neuropsychological tests
- **OTHER:** MRI Scan - Arterial Spin Labelling

## Key facts

- **NCT ID:** NCT02450253
- **Lead sponsor:** St George's, University of London
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-09
- **Primary completion:** 2018-01-25
- **Final completion:** 2018-01-25
- **Target enrollment:** 55 (ACTUAL)
- **Last updated:** 2022-10-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02450253

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02450253, "Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02450253. Licensed CC0.

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