# A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacology of ONO-4474 in Healthy Volunteers

> **NCT02454387** · PHASE1 · COMPLETED · sponsor: **Ono Pharmaceutical Co., Ltd.** · enrollment: 141 (actual)

## Conditions studied

- Osteoarthritis

## Interventions

- **DRUG:** ONO-4474 Part A1
- **DRUG:** Placebo Part A1
- **DRUG:** ONO-4474 Part A2
- **DRUG:** Placebo Part A2
- **DRUG:** ONO-4474 Part B
- **DRUG:** Placebo Part B
- **DRUG:** ONO-4474 Part C
- **DRUG:** Placebo Part C
- **DRUG:** ONO-4474 Part D
- **DRUG:** Placebo Part D

## Key facts

- **NCT ID:** NCT02454387
- **Lead sponsor:** Ono Pharmaceutical Co., Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-05
- **Primary completion:** 2016-04
- **Final completion:** 2016-04
- **Target enrollment:** 141 (ACTUAL)
- **Last updated:** 2016-06-30


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02454387

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02454387, "A Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacology of ONO-4474 in Healthy Volunteers". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT02454387. Licensed CC0.

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