# Incretin-based Drugs and the Risk of Heart Failure

> **NCT02456428** · — · COMPLETED · sponsor: **Canadian Network for Observational Drug Effect Studies, CNODES** · enrollment: 1499650 (actual)

## Conditions studied

- Type 2 Diabetes Mellitus

## Interventions

- **DRUG:** DPP-4 inhibitors
- **DRUG:** GLP-1 analogs
- **DRUG:** Insulins
- **DRUG:** Biguanides
- **DRUG:** Sulfonylureas
- **DRUG:** Thiazolidinediones
- **DRUG:** Alpha-glucosidase inhibitors
- **DRUG:** Meglitinides

## Key facts

- **NCT ID:** NCT02456428
- **Lead sponsor:** Canadian Network for Observational Drug Effect Studies, CNODES
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** COMPLETED
- **Start date:** 2014-03
- **Primary completion:** 2015-05
- **Final completion:** 2015-05
- **Target enrollment:** 1499650 (ACTUAL)
- **Last updated:** 2016-04-19

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02456428

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02456428, "Incretin-based Drugs and the Risk of Heart Failure". Retrieved via AI Analytics 2026-06-12 from https://api.ai-analytics.org/clinical/NCT02456428. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*