# Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients

> **NCT02456844** · PHASE1 · COMPLETED · sponsor: **Bristol-Myers Squibb** · enrollment: 24 (actual)

## Conditions studied

- Rheumatoid Arthritis

## Interventions

- **DRUG:** Montelukast, Flurbiprofen, Midazolam, Digoxin, Pravastatin and BMS-986142
- **DRUG:** Methotrexate, Leucovorin and BMS-986142

## Key facts

- **NCT ID:** NCT02456844
- **Lead sponsor:** Bristol-Myers Squibb
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-05
- **Primary completion:** 2015-07
- **Final completion:** 2015-07
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2016-02-01


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02456844

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02456844, "Study to Investigate the Effect of BMS-986142 on the Pharmacokinetics (PK) of Methotrexate and Probe Substrate Cocktail in Healthy Patients". Retrieved via AI Analytics 2026-07-11 from https://api.ai-analytics.org/clinical/NCT02456844. Licensed CC0.

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