# The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43

> **NCT02457104** · — · UNKNOWN · sponsor: **University of Colorado, Denver** · enrollment: 120 (estimated)

## Conditions studied

- Gastroesophageal Reflux Disease
- Obesity

## Interventions

- **PROCEDURE:** Colonoscopy
- **BEHAVIORAL:** Weight and diet questionnaire

## Key facts

- **NCT ID:** NCT02457104
- **Lead sponsor:** University of Colorado, Denver
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** UNKNOWN
- **Start date:** 2015-06
- **Primary completion:** 2021-10
- **Final completion:** 2021-12
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2021-02-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02457104

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02457104, "The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT02457104. Licensed CC0.

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