# Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors

> **NCT02458339** · PHASE1 · COMPLETED · sponsor: **The University of Texas Health Science Center, Houston** · enrollment: 7 (actual)

## Conditions studied

- Brain Tumor, Recurrent
- Malignant Neoplasm of Fourth Ventricle of Brain

## Interventions

- **PROCEDURE:** Ommaya Reservoir
- **DRUG:** Methotrexate

## Key facts

- **NCT ID:** NCT02458339
- **Lead sponsor:** The University of Texas Health Science Center, Houston
- **Sponsor class:** OTHER
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-06-15
- **Primary completion:** 2019-03-01
- **Final completion:** 2019-03-01
- **Target enrollment:** 7 (ACTUAL)
- **Last updated:** 2019-03-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02458339

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02458339, "Methotrexate Infusion Into Fourth Ventricle in Children With Recurrent Malignant Fourth Ventricular Brain Tumors". Retrieved via AI Analytics 2026-05-31 from https://api.ai-analytics.org/clinical/NCT02458339. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*
