# Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial

> **NCT02462590** · PHASE4 · COMPLETED · sponsor: **McMaster University** · enrollment: 2650 (estimated)

## Conditions studied

- Ventilator Associated Pneumonia
- Infections
- C-Difficile
- Antibiotic-associated Diarrhea
- Diarrhea

## Interventions

- **DRUG:** L. rhamnosus GG - Probiotic
- **DRUG:** Placebo - Microcrystalline Cellulose

## Key facts

- **NCT ID:** NCT02462590
- **Lead sponsor:** McMaster University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-06
- **Primary completion:** 2019-03-13
- **Final completion:** 2020-11-17
- **Target enrollment:** 2650 (ESTIMATED)
- **Last updated:** 2020-12-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02462590

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02462590, "Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial". Retrieved via AI Analytics 2026-05-30 from https://api.ai-analytics.org/clinical/NCT02462590. Licensed CC0.

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