# Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer

> **NCT02473094** · PHASE2 · TERMINATED · sponsor: **University of Campinas, Brazil** · enrollment: 3 (actual)

## Conditions studied

- Rectal Neoplasms
- Adenocarcinoma
- Carcinoma

## Interventions

- **DRUG:** Capecitabine
- **DRUG:** Metformin
- **RADIATION:** Radiotherapy
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02473094
- **Lead sponsor:** University of Campinas, Brazil
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2015-07
- **Primary completion:** 2016-02
- **Final completion:** 2016-02
- **Target enrollment:** 3 (ACTUAL)
- **Why stopped:** Slow Accrual
- **Last updated:** 2017-11-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02473094

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02473094, "Neoadjuvant Metformin in Association to Chemoradiotherapy for Locally Advanced Rectal Cancer". Retrieved via AI Analytics 2026-07-04 from https://api.ai-analytics.org/clinical/NCT02473094. Licensed CC0.

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