# Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism

> **NCT02500342** · PHASE4 · COMPLETED · sponsor: **Insel Gruppe AG, University Hospital Bern** · enrollment: 276 (actual)

## Conditions studied

- Thyroid Dysfunction
- Mental Fatigue
- Fatigue

## Interventions

- **DRUG:** Levothyroxine
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02500342
- **Lead sponsor:** Insel Gruppe AG, University Hospital Bern
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2014-01
- **Primary completion:** 2018-04-05
- **Final completion:** 2018-04-05
- **Target enrollment:** 276 (ACTUAL)
- **Last updated:** 2019-03-29

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02500342

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02500342, "Effect of Thyroid Hormone Replacement on Fatigability in Untreated Older Adults With Subclinical Hypothyroidism". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT02500342. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*