# Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer

> **NCT02506790** · PHASE2 · UNKNOWN · sponsor: **N.N. Petrov National Medical Research Center of Oncology** · enrollment: 96 (estimated)

## Conditions studied

- Breast Cancer

## Interventions

- **DRUG:** metformin
- **DRUG:** Melatonin
- **DRUG:** Toremifene

## Key facts

- **NCT ID:** NCT02506790
- **Lead sponsor:** N.N. Petrov National Medical Research Center of Oncology
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2015-07
- **Primary completion:** 2020-08
- **Final completion:** 2022-08
- **Target enrollment:** 96 (ESTIMATED)
- **Last updated:** 2019-09-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02506790

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02506790, "Neoadjuvant Toremifene With Melatonin or Metformin in Locally Advanced Breast Cancer". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT02506790. Licensed CC0.

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