Sanaria PfSPZ Challenge With Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge With Concurrent Pyrimethamine Treatment That Inhibits Development of Asexual B...

NCT02511054 · clinicaltrials.gov ↗

PHASE1

Phase

COMPLETED

Status

57

Enrollment

NIH

Sponsor class

Conditions

Malaria

Interventions

DRUG: Chloroquine (CQ)
DRUG: Pyrimethamine (PYR)
BIOLOGICAL: Sanaria PfSPZ Challenge (NF54)

Sponsor

National Institute of Allergy and Infectious Diseases (NIAID)