# A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54175446 in Healthy Male Participants

> **NCT02515955** · PHASE1 · COMPLETED · sponsor: **Janssen-Cilag International NV** · enrollment: 76 (actual)

## Conditions studied

- Healthy

## Interventions

- **DRUG:** JNJ-54175446
- **DRUG:** Minocycline
- **DRUG:** JNJ 54175446 Matching Placebo
- **DRUG:** D Amphetamine
- **DRUG:** D Amphetamine Matching Placebo

## Key facts

- **NCT ID:** NCT02515955
- **Lead sponsor:** Janssen-Cilag International NV
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-08
- **Primary completion:** 2016-03
- **Final completion:** 2016-03
- **Target enrollment:** 76 (ACTUAL)
- **Last updated:** 2025-02-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02515955

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02515955, "A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-54175446 in Healthy Male Participants". Retrieved via AI Analytics 2026-05-25 from https://api.ai-analytics.org/clinical/NCT02515955. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*