Response-Based Chemotherapy in Treating Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome in Younger Patients With Down Syndrome

NCT02521493 · clinicaltrials.gov ↗

PHASE3

Phase

ACTIVE_NOT_RECRUITING

Status

280

Enrollment

NETWORK

Sponsor class

Conditions

Acute Myeloid Leukemia
Down Syndrome
Myelodysplastic Syndrome
Myeloid Leukemia Associated With Down Syndrome
Myeloproliferative Neoplasm

Interventions

DRUG: Asparaginase
DRUG: Asparaginase Erwinia chrysanthemi
DRUG: Cytarabine
DRUG: Daunorubicin Hydrochloride
DRUG: Etoposide
OTHER: Laboratory Biomarker Analysis
DRUG: Mitoxantrone Hydrochloride
DRUG: Thioguanine

Sponsor

Children's Oncology Group

Collaborators

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