Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis
Stopped The study design was revised so a new protocol will be opened.
Conditions
- Acute Myeloid Leukemia in Remission
- Primary Myelofibrosis
- Primary Myelofibrosis, Prefibrotic Stage
- Secondary Acute Myeloid Leukemia
- Secondary Myelofibrosis
Interventions
- PROCEDURE: Allogeneic Bone Marrow Transplantation
- PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
- DRUG: Fludarabine Phosphate
- OTHER: Laboratory Biomarker Analysis
- DRUG: Melphalan
- PROCEDURE: Peripheral Blood Stem Cell Transplantation
- OTHER: Pharmacological Study
- DRUG: Ruxolitinib Phosphate
- DRUG: Sirolimus
- DRUG: Tacrolimus
Sponsor
City of Hope Medical Center
Collaborators