# Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation

> **NCT02538367** · PHASE1,PHASE2 · COMPLETED · sponsor: **Yuhan Corporation** · enrollment: 120 (actual)

## Conditions studied

- Functional Constipation

## Interventions

- **DRUG:** YH12852 IR 0.05mg
- **DRUG:** YH12852 IR 0.1mg
- **DRUG:** YH12852 IR 0.3mg
- **DRUG:** YH12852 IR 0.5mg
- **DRUG:** YH12852 IR 1mg
- **DRUG:** YH12852 IR 2mg
- **DRUG:** YH12852 IR 3mg
- **DRUG:** YH12852 DR1 0.5mg
- **DRUG:** YH12852 DR1 1mg
- **DRUG:** YH12852 DR1 2mg
- **DRUG:** YH12852 DR1 4mg
- **DRUG:** YH12852 DR2 8mg
- **DRUG:** Prucalopride 2mg
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02538367
- **Lead sponsor:** Yuhan Corporation
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1,PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-08
- **Primary completion:** 2016-09
- **Final completion:** 2016-09
- **Target enrollment:** 120 (ACTUAL)
- **Last updated:** 2016-10-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02538367

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02538367, "Phase 1/2a Trial of YH12852 in Healthy Subjects and Patients With Functional Constipation". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02538367. Licensed CC0.

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