# Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty

> **NCT02570503** · PHASE4 · TERMINATED · sponsor: **Virginia Commonwealth University** · enrollment: 64 (actual)

## Conditions studied

- Osteoarthritis, Knee

## Interventions

- **DRUG:** Ropivacaine
- **DRUG:** Ketorolac
- **DRUG:** Clonidine
- **DRUG:** Epinephrine
- **DRUG:** 0.9% sodium chloride

## Key facts

- **NCT ID:** NCT02570503
- **Lead sponsor:** Virginia Commonwealth University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2015-10
- **Primary completion:** 2021-02-11
- **Final completion:** 2021-02-11
- **Target enrollment:** 64 (ACTUAL)
- **Why stopped:** Study's primary aims are no longer clinically impactful, as intrathecal morphine has fallen out of favor and replaced with different agents so that outpatient/23 hr surgery is more predictably achievable.
- **Last updated:** 2022-03-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02570503

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02570503, "Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT02570503. Licensed CC0.

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