# A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects

> **NCT02571855** · PHASE1 · COMPLETED · sponsor: **Idorsia Pharmaceuticals Ltd.** · enrollment: 85 (actual)

## Conditions studied

- Healthy Subjects

## Interventions

- **DRUG:** ACT-541468 (hydrochloride salt)
- **DRUG:** ACT-541468 (free base)
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT02571855
- **Lead sponsor:** Idorsia Pharmaceuticals Ltd.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2015-10-01
- **Primary completion:** 2016-02-01
- **Final completion:** 2016-02-01
- **Target enrollment:** 85 (ACTUAL)
- **Last updated:** 2018-07-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02571855

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02571855, "A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of ACT-541468 in Healthy Young Adults and Elderly Subjects". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT02571855. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*