# Clinical Benefits of the Closed Loop Stimulation in Sinus Node Disease

> **NCT02579889** · NA · TERMINATED · sponsor: **Biotronik SE & Co. KG** · enrollment: 1390 (actual)

## Conditions studied

- Sinus Node Disease

## Interventions

- **DEVICE:** DDD+CLS
- **DEVICE:** DDD(R)

## Key facts

- **NCT ID:** NCT02579889
- **Lead sponsor:** Biotronik SE & Co. KG
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2015-09
- **Primary completion:** 2023-03
- **Final completion:** 2023-12
- **Target enrollment:** 1390 (ACTUAL)
- **Why stopped:** Stopping criterion met (N. adjudicated EP1)
- **Last updated:** 2024-01-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT02579889

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT02579889, "Clinical Benefits of the Closed Loop Stimulation in Sinus Node Disease". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT02579889. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*